Retatrutide vs Contrave: Not Even Close
Retatrutide (peptide, 24-28% loss) vastly outperforms Contrave (naltrexone/bupropion pill, 5-9% loss). Different class of medication entirely.
| Feature | Retatrutide | Contrave |
|---|---|---|
| Weight Loss | 24-28.7% | 5-9% |
| Mechanism | Triple agonist peptide | Naltrexone + Bupropion |
| Delivery | Weekly injection | 2 pills twice daily |
| Cost | $400-700/mo (est.) | $100-300/mo |
Why Contrave Is Obsolete
Contrave was "good" before GLP-1 peptides existed. Now it's completely outclassed:
- • 3-5x LESS effective: 5-9% vs 24-28% with retatrutide
- • Old mechanism: Works on appetite/cravings, not metabolic hormones
- • More side effects: Nausea, headaches, constipation, seizure risk
- • Daily pills: 4 pills/day vs 1 injection/week
Better option: Save up for tirzepatide ($179-499/mo) instead of wasting money on Contrave.
Skip Contrave—Get Real Peptides
Tirzepatide: 15-22.5% loss (3x better than Contrave), $179-499/mo.
Start Tirzepatide →